Results
Results list研究成果一覧
謝辞の記載についてAcknowledgement remarks
雑誌論文Papers
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Miki Nakano, Osamu Miyashita, Yasumasa Joti, Akihiro Suzuki, Hideyuki Mitomo, Yoshiya Niida, Ying Yang, Hirokatsu Yumoto, Takahisa Koyama, Kensuke Tono, Haruhiko Ohashi, Makina Yabashi, Tetsuya Ishikawa, Yoshitaka Bessho, Kuniharu Ijiro, Yoshinori Nishino, Florence Tama
Three-dimensional structure determination of gold nanotriangles in solution using X-ray free-electron laser single-particle analysis
Optica , 9 , 7 , 776 (2022)
DOI: https://doi.org/10.1364/optica.457352
プレスリリース: https://www.riken.jp/press/2022/20220715_2/index.html
A01: C01: B01:2022 A01 Yoshitaka Bessho C01 Osamu Miyashita B01 Akihiro Suzuki -
Akihiro Suzuki, Hiromochi Tanaka, Hisao Yamashige, Yuki Orikasa, Yoshiya Niida, Takashi Kimura, Kensuke Tono, Makina Yabashi, Tetsuya Ishikawa, Yoshitaka Bessho, Yasumasa Joti, Yoshinori Nishino
Femtosecond X-ray Laser Reveals Intact Sea–Island Structures of Metastable Solid-State Electrolytes for Batteries
Nano Letters , 22 , 11 , 4603 (2022)
DOI: https://doi.org/10.1021/acs.nanolett.1c04392
プレスリリース: https://www.hokudai.ac.jp/news/2022/05/xx.html
A01: B01:2022 A01 Yoshitaka Bessho B01 Akihiro Suzuki -
Jinta Asami, Jae-Hyun Park, Yayoi Nomura, Chisa Kobayashi, Junki Mifune, Naito Ishimoto, Tomoko Uemura, Kehong Liu, Yumi Sato, Zhikuan Zhang, Masamichi Muramatsu, Takaji Wakita, David Drew, So Iwata, Toshiyuki Shimizu, Koichi Watashi, Sam-Yong Park, Norimichi Nomura, Umeharu Ohto
Structural basis of hepatitis B virus receptor binding
Nature Structural & Molecular Biology , 31 (2024)
DOI: 10.1038/s41594-023-01191-5
プレスリリース:
A01: A01 So Iwata A01 Norimichi Nomura A01 Sam-Yong Park -
*Maestre-Reyna M, Wang PH, Nango E, Hosokawa Y, Saft M, Furrer A, Yang CH, Gusti Ngurah Putu EP, Wu WJ, Emmerich HJ, Caramello N, Franz-Badur S, Yang C, Engilberge S, Wranik M, Glover HL, Weinert T, Wu HY, Lee CC, Huang WC, Huang KF, Chang YK, Liao JH, Weng JH, Gad W, Chang CW, Pang AH, Yang KC, Lin WT, Chang YC, Gashi D, Beale E, Ozerov D, Nass K, Knopp G, Johnson PJM, Cirelli C, Milne C, Bacellar C, Sugahara M, Owada S, Joti Y, Yamashita A, Tanaka R, Tanaka T, Luo F, Tono K, Zarzycka W, Muller P, Alahmad MA, Bezold F, Fuchs V, Gnau P, Kiontke S, Korf L, Reithofer V, Rosner CJ, Seiler EM, Watad M, Werel L, Spadaccini R, Yamamoto J, Iwata S, Zhong D, Standfuss J, Royant A, *Bessho Y, *Essen LO, *Tsai MD.
Visualizing the DNA repair process by a photolyase at atomic resolution.
J Science , 382 , 6674 , eadd7795 (2023)
DOI: https://doi.org/10.1126/science.add7795
プレスリリース: https://www.riken.jp/press/2023/20231201_2/index.html
A01: B01: A01 So Iwata A01 Yoshitaka Bessho B01 Eriko Nango B01 Sigeki Owada -
Han Ba Bui, Satoshi Watanabe, Norimichi Nomura, Kehong Liu, Tomoko Uemura, Michio Inoue, Akihisa Tsutsumi, Hiroyuki Fujita, Kengo Kinoshita, Yukinari Kato, So Iwata, Masahide Kikkawa, Kenji Inaba
Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn2+ uptake into the Golgi apparatus
Nature Communications , 14 , 4770 (2023)
DOI: 10.1038/s41467-023-40521-5
A01: A01 So Iwata A01 Norimichi Nomura -
Naito Ishimoto, Jae-Hyun Park, Kouki Kawakami, Michiko Tajiri, Kenji Mizutani, Satoko Akashi, Jeremy R. H. Tame, Asuka Inoue, Sam-Yong Park
Structural basis of CXC chemokine receptor 1 ligand binding and activation
Nat Commun. , 14 , 4107 (2023)
DOI: https://doi.org/10.1038/s41467-023-39799-2
プレスリリース: https://www.yokohama-cu.ac.jp/news/2023/20230728park.html
A01: A01 Sam-Yong Park -
Titouan Jaunet-Lahary, Tatsuro Shimamura, Masahiro Hayashi, Norimichi Nomura, Kouta Hirasawa, Tetsuya Shimizu, Masao Yamashita, Naotaka Tsutsumi, Yuta Suehiro, Keiichi Kojima, Yuki Sudo, Takashi Tamura, Hiroko Iwanari, Takao Hamakubo, So Iwata, Kei-ichi Okazaki, Teruhisa Hirai, Atsuko Yamashita
Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota
Nature Communications , 14 , 1730 (2023)
DOI: https://doi.org/10.1038/s41467-023-36883-5
A01: A01 So Iwata A01 Norimichi Nomura -
Haruyo Hatanaka, Hiromi Toyonaga, Yukiko Ishida, Eiichi Mizohata, Eiichiro Ono
Functional diversity and plasticity in the sugar preferences of Saccharomyces MALT transporters in domesticated yeasts
FEMS Yeast Res. , 22 , 1 , foac055 (2022)
DOI: 10.1093/femsyr/foac055.
A01: A01 Eiichi Mizohata -
Muna Al-Habsi, Kenji Chamoto, Ken Matsumoto, Norimichi Nomura, Baihao Zhang, Yuki Sugiura, Kazuhiro Sonomura, Aprilia Maharani, Yuka Nakajima, Yibo Wu, Yayoi Nomura, Rosemary Menzies, Masaki Tajima, Koji Kitaoka, Yasuharu Haku, Sara Delghandi, Keiko Yurimoto, Fumihiko Matsuda, So Iwata, Toshihiko Ogura, Sidonia Fagarasan, Tasuku Honjo
Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice
Science , 378 , 6618 , eabj3510 (2022)
DOI: 10.1126/science.abj3510
A01: A01 So Iwata A01 Norimichi Nomura -
Ryoji Suno, Yukihiko Sugita, Kazushi Morimoto, Hiroko Takazaki, Hirokazu Tsujimoto, Mika Hirose, Chiyo Suno-Ikeda, Norimichi Nomura, Tomoya Hino, Asuka Inoue, Kenji Iwasaki, Takayuki Kato, So Iwata, Takuya Kobayashi
Structural insights into the G protein selectivity revealed by the human EP3-Gi signaling complex
Cell Reports , 40 , 11 , 111323 (2022)
DOI: 10.1016/j.celrep.2022.111323
プレスリリース:
A01: A01 So Iwata A01 Norimichi Nomura A01 Tomoya Hino -
Zhikuan Zhang, Norimichi Nomura, Yukiko Muramoto, Toru Ekimoto, Tomoko Uemura, Kehong Liu, Moeko Yui, Nozomu Kono, Junken Aoki, Mitsunori Ikeguchi, Takeshi Noda, So Iwata, Umeharu Ohto, Toshiyuki Shimizu
Structure of SARS-CoV-2 membrane protein essential for virus assembly
Nature Communications , 13 , 4399 (2022)
DOI: 10.1038/s41467-022-32019-3
プレスリリース:
A01: A01 So Iwata A01 Norimichi Nomura -
Jinta Asami, Kanako Terakado Kimura, Yoko Fujita-Fujiharu, Hanako Ishida, Zhikuan Zhang, Yayoi Nomura, Kehong Liu, Tomoko Uemura, Yumi Sato, Masatsugu Ono, Masaki Yamamoto, Takeshi Noda, Hideki Shigematsu, David Drew, So Iwata, Toshiyuki Shimizu, Norimichi Nomura, Umeharu Ohto
Structure of the bile acid transporter and HBV receptor NTCP
Nature , 606 , 7916 , 1021 (1026)
DOI: https://doi.org/10.1038/s41586-022-04845-4
A01: B01: A01 So Iwata A01 Norimichi Nomura B01 Masaki Yamamoto -
Jae-Hyun Park, Masashi Iwamoto, Ji-Hye Yun, Tomomi Uchikubo-Kamo, Donghwan Son, Zeyu Jin, Hisashi Yoshida, Mio Ohki, Naito Ishimoto, Kenji Mizutani, Mizuki Oshima, Masamichi Muramatsu, Takaji Wakita, Mikako Shirouzu, Kehong Liu, Tomoko Uemura, Norimichi Nomura, So Iwata, Koichi Watashi, Jeremy R. H. Tame, Tomohiro Nishizawa, Weontae Lee, Sam-Yong Park
Structural insights into the HBV receptor and bile acid transporter NTCP
Nature , 606 , 7916 , 1027-1031 (2022)
DOI: https://doi.org/10.1038/s41586-022-04857-0
プレスリリース: https://www.yokohama-cu.ac.jp/news/2022/20220518parksamyong.html
A01: A01 So Iwata A01 Norimichi Nomura A01 Sam-Yong Park -
*Wakao Fukuda, Mamoru Osaki, Yusuke Yasuda, Ryota Hidese , Tsunehiko Higuchi, Naoki Umezawa, Shinsuke Fujiwara and *Eiichi Mizohata
Substrate Specificity of an Aminopropyltransferase and the Biosynthesis Pathway of Polyamines in the Hyperthermophilic Crenarchaeon Pyrobaculum calidifontis
Catalysts , 12 , 5 , 567 (2022)
DOI: 10.3390/catal12050567
A01: A01 Eiichi Mizohata -
Hosaka T, Nomura T, Kubo M, Nakane T, Fangjia L, Sekine SI, Ito T, Murayama K, Ihara K, Ehara H, Kashiwagi K, Katsura K, Akasaka R, Hisano T, Tanaka T, Tanaka R, Arima T, Yamashita A, Sugahara M, Naitow H, Matsuura Y, Yoshizawa S, Tono K, Owada S, Nureki O, Kimura-Someya T, Iwata S, *Nango E, *Shirouzu M.
Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers
Proc Natl Acad Sci U S A , 119 , 9 , e2117433119 (2022)
DOI: https://doi.org/10.1073/pnas.2117433119
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2022-02-28-2
A01: B01: C01: A01:2020 A01 So Iwata B01 Eriko Nango B01 Sigeki Owada C01 Minoru Kubo A01 Toshiaki Hosaka -
Rei Matsuoka, Roman Fudim, Sukkyeong Jung, Chenou Zhang, Andre Bazzone, Yurie Chatzikyriakidou, Carol V. Robinson, Norimichi Nomura, So Iwata, Michael Landreh, Laura Orellana, Oliver Beckstein, David Drew
Structure, mechanism and lipid-mediated remodeling of the mammalian Na+/H+ exchanger NHA2
Nature Structural & Molecular Biology , 29 , 2 , 108-120 (2022)
DOI: 10.1038/s41594-022-00738-2
A01: A01 So Iwata A01 Norimichi Nomura -
Koichiro E. Kishi, Yoon Seok Kim, Masahiro Fukuda, Masatoshi Inoue, Tsukasa Kusakizako, Peter Y. Wang, Charu Ramakrishnan, Eamon F.X. Byrne, Elina Thadhani, Joseph M. Paggi, Toshiki E. Matsui, Keitaro Yamashita, Takashi Nagata, Masae Konno, Sean Quirin, Maisie Lo, Tyler Benster, Tomoko Uemura, Kehong Liu, Mikihiro Shibata, Norimichi Nomura, So Iwata, Osamu Nureki, Ron O. Dror, Keiichi Inoue, Karl Deisseroth, Hideaki E. Kato
Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine
Cell , 185 , 4 , 672-689 (2022)
DOI: 10.1016/j.cell.2022.01.007
プレスリリース: https://www.u-tokyo.ac.jp/focus/ja/press/z0109_00034.html
A01: A01 So Iwata A01 Norimichi Nomura A01 Tsukasa Kusakizako A01 Keitaro Yamashita -
Pan D, Oyama R, Sato T, Nakane T, Mizunuma R, Matsuoka K, Joti Y, Tono K, Nango E, Iwata S, Nakatsu T and *Kato H.
Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX
IUCrJ. , 9 , 1 (2021)
DOI: https://doi.org/10.1107/S2052252521011611
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2021-12-23
A01: B01: A01 So Iwata A01 Toru Nakatsu B01 Eriko Nango -
*Katayama K, Suzuki K, Suno R, Kise R, Tsujimoto H, Iwata S, Inoue A, Kobayashi T & *Kandori H.
Vibrational spectroscopy analysis of ligand efficacy in human M2 muscarinic acetylcholine receptor (M2R)
Communications Biology , 4 , 1321 (2021)
DOI: https://doi.org/10.1038/s42003-021-02836-1
プレスリリース: https://www.nitech.ac.jp/news/press/2021/9297.html
A01: A01:2020 A01 So Iwata A01 Kota Katayama -
Shinya Hanashima, Takanori Nakane, *Eiichi Mizohata
Heavy Atom Detergent/Lipid Combined X-ray Crystallography for Elucidating Structure-function Relationships of Membrane Proteins
Membranes , 11 , 11 , 823 (2021)
DOI: 10.3390/membranes11110823
A01: A01 Eiichi Mizohata -
1. *Murakaw T, Suzuki M, Arima T, Sugahara M, Tanaka T, Tanaka R, Iwata S, Nango E, Tono K, Hayashi H, Fukui K, Yano T, Tanizawah K and *Okajima T.
Microcrystal preparation for serial femtosecond X-ray crystallography of bacterial copper amine oxidase
Acta Crystallographica Section F. , 77 (2021)
DOI: https://doi.org/10.1107/S2053230X21008967
A01: B01: A01:2020 A01 So Iwata B01 Eriko Nango A01 Takeshi Murakawa -
Dmitry Ghilarov, Satomi Inaba-Inoue, Piotr Stepien, Feng Qu, Elizabeth Michalczyk, Zuzanna Pakosz, Norimichi Nomura, Satoshi Ogasawara, Graham Charles Walker, Sylvie Rebuffat, So Iwata, Jonathan Gardiner Heddle, Konstantinos Beis
Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides
Science Advances , 7 , 37 , abj5363 (2021)
DOI: 10.1126/sciadv.abj5363
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2021-09-09-0
A01: A01 So Iwata A01 Norimichi Nomura -
Hiroyuki H. Okamoto, Hirotake Miyauchi, Asuka Inoue, Francesco Raimondi, Hirokazu Tsujimoto, Tsukasa Kusakizako, Wataru Shihoya, Keitaro Yamashita, Ryoji Suno, Norimichi Nomura, Takuya Kobayashi, So Iwata, Tomohiro Nishizawa, Osamu Nureki
Cryo-EM structure of the human MT1–Gi signaling complex
Nature Structural & Molecular Biology , 28 (2021)
DOI: 10.1038/s41594-021-00634-1
プレスリリース: https://www.s.u-tokyo.ac.jp/ja/info/7508/
A01: A01:2020 A01 So Iwata A01 Norimichi Nomura A01 Tsukasa Kusakizako A01 Keitaro Yamashita A01 Wataru Shihoya -
Shingo Nojima, Yoko Fujita, Kanako Terakado Kimura, Norimichi Nomura, Ryoji Suno, Kazushi Morimoto, Masaki Yamamoto, Takeshi Noda, So Iwata, Hideki Shigematsu, Takuya Kobayashi
Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein
Structure , 29 , 3 , 252-260 (2021)
DOI: 10.1016/j.str.2020.11.007
A01: B01: A01 So Iwata A01 Norimichi Nomura B01 Masaki Yamamoto -
Stephanie L. Neville, Jennie Sjöhamn, Jacinta A. Watts, Hugo MacDermott-Opeskin, Stephen J. Fairweather, Katherine Ganio, Alex Carey Hulyer, Aaron P. McGrath, Andrew J. Hayes, Tess R. Malcolm, Mark R. Davies, Norimichi Nomura, So Iwata, Megan L. O’Mara, Megan J. Maher, Christopher A. McDevitt
The structural basis of bacterial manganese import
Science Advances , 7 , 32 , eabg3980 (2021)
DOI: 10.1126/sciadv.abg3980
A01: A01 So Iwata A01 Norimichi Nomura -
Fujiyama K, Kato N, Re S, Kinugasa K, Watanabe K, Takita R, Nogawa T, Hino T, Osada H, Sugita Y, Takahashi S, Nagano S.
Molecular basis for two stereoselective Diels-Alderases that produce decalin skeletons.
Angew Chem Int Ed. (2021)
DOI: https://doi.org/10.1002/anie.202106186
プレスリリース: https://www.tottori-u.ac.jp/item/18745.htm
A01: A01:2020 A01 Shingo Nagano A01 Tomoya Hino -
Demura K, Kusakizako T, Shihoya W, Hiraizumi M, Nomura K, Shimada H, Yamashita K, Nishizawa T, Taruno A, Nureki O.
Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies
Sci Adv. , 6 , 29 , eaba8105 (2020)
DOI: 10.1126/sciadv.aba8105.
A01: A01:2020 A01 Tsukasa Kusakizako A01 Wataru Shihoya -
Fukuhara S, Kobayashi K, Kusakizako T, Iida W, Kato M, Shihoya W, Nureki O.
Structure of the human secretin receptor coupled to an engineered heterotrimeric G protein
Biochem Biophys Res Commun , 533 , 4 , 861-866 (2020)
DOI: 10.1016/j.bbrc.2020.08.042.
A01: A01:2020 A01 Tsukasa Kusakizako A01 Wataru Shihoya -
Oda K, Nomura T, Nakane T, Yamashita K, Inoue K, Ito S, Vierock J, Hirata K, Maturana AD, Katayama K, Ikuta T, Ishigami I, Izume T, Umeda R, Eguma R, Oishi S, Kasuya G, Kato T, Kusakizako T, Shihoya W, Shimada H, Takatsuji T, Takemoto M, Taniguchi R, Tomita A, Nakamura R, Fukuda M, Miyauchi H, Lee Y, Nango E, Tanaka R, Tanaka T, Sugahara M, Kimura T, Shimamura T, Fujiwara T, Yamanaka Y, Owada S, Joti Y, Tono K, Ishitani R, Hayashi S, Kandori H, Hegemann P, Iwata S, Kubo M, Nishizawa T, Nureki O.
Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin
elife , 23 , e62389 (2021)
DOI: 10.7554/eLife.62389
プレスリリース: https://www.s.u-tokyo.ac.jp/ja/press/2021/7284/
A01: B01: C01: A01:2020 C01:2020 A01 So Iwata A01 Tsukasa Kusakizako B01 Eriko Nango B01 Sigeki Owada C01 Minoru Kubo C01 Tetsunari Kimura A01 Wataru Shihoya A01 Kota Katayama C01 Shigehiko Hayashi -
Jin F, Sun M, Fujii T, Yamada Y, Wang J, Maturana AD, Wada M, Su S, Ma J, Takeda H, Kusakizako T, Tomita A, Nakada-Nakura Y, Liu K, Uemura T, Nomura Y, Nomura N, Ito K, Nureki O, Namba K, Iwata S, Yu Y, Hattori M
The structure of MgtE in the absence of magnesium provides new insights into channel gating
PLOS Biology , 19 , 4 , e3001231 (2021)
DOI: 10.1371/journal.pbio.3001231
A01: A01 So Iwata A01 Norimichi Nomura -
Matoba K, Kotani T, Tsutsumi A, Tsuji T, Mori T, Noshiro D, Sugita Y, Nomura N, Iwata S, Ohsumi Y, Fujimoto T, Nakatogawa H, Kikkawa M, Noda NN
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion
Nature Structural & Molecular Biology , 27 , 1185-1193 (2020)
DOI: 10.1038/s41594-020-00518-w
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2020-10-28
A01: A01 So Iwata A01 Norimichi Nomura -
Umeda R, Satouh Y, Takemoto M, Nakada-Nakura Y, Liu K, Yokoyama T, Shirouzu M, Iwata S, Nomura N, Sato K, Ikawa M, Nishizawa T, Nureki O
Structural insights into tetraspanin CD9 function
Nature Communications , 11 , 1606 (2020)
DOI: 10.1038/s41467-020-15459-7
A01: A01 So Iwata A01 Norimichi Nomura -
Asada H, Inoue A, Ngako Kadji FM, Hirata K, Shiimura Y, Im D, Shimamura T, Nomura N, Iwanari H, Hamakubo T, Kusano-Arai O, Hisano H, Uemura T, Suno C, Aoki J and Iwata S
The crystal structure of angiotensin II type 2 receptor with endogenous peptide hormone
Structure , 28 , 4 , 418-425 (2020)
DOI: 10.1016/j.str.2019.12.003
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2020-01-22-1
A01: A01 So Iwata A01 Norimichi Nomura -
Kinjo T, Terai K, Horita S, Nomura N, Sumiyama K, Togashi K, Iwata S and Matsuda M.
FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics
Nature Methods , 16 , 1029-1036 (2019)
DOI: 10.1038/s41592-019-0541-5
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2019-09-10
A01: A01 So Iwata A01 Norimichi Nomura -
Toyomoto M, Inoue A, Iida K, Denawa M, Kii I, Ngako Kadji FM, Kishi T, Im D, Shimamura T, Onogi H, Yoshida S, Iwata S, Aoki J, Hosoya T, Hagiwara M.
S1PR3-G 12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation
Cell Chem Biol. , 28 , 1-13 (2021)
DOI: 10.1016/j.chembiol.2021.01.004.
A01: A01 So Iwata -
Suga, M., Akita, F., Yamashita, K., Nakajima, Y., Ueno, G., Li, H., Yamane, T., Hirata, K., Umena, Y., Yonekura, S., Yu, L.-J., Murakami, H., Nomura, T., Kimura, T., Kubo, M., Baba, S., Kumasaka, T., Tono, K., Yabashi, M., Isobe, H., Yamaguchi, K. Yamamoto, M., Ago, H., Shen, J.-R.
An oxyl/oxo mechanism for oxygen-oxygen coupling in PSII revealed by an X-ray free electron laser.
Science , 366 , 6463 , 334-338 (2019)
DOI: 10.1126/science.aax6998
A01: B01: C01: A01:2020 A01 Yasufumi Umena B01 Masaki Yamamoto B01 Kumasaka Takashi C01 Minoru Kubo C01 Tetsunari Kimura A01 Michihiro Suga -
Im D, Inoue A, Fujiwara T, Nakane T, Yamanaka Y, Uemura T, Mori C, Shiimura Y, Kimura KT, Asada H, Nomura N, Tanaka T, Yamashita A, Nango E, Tono K, Kadji FMN, Aoki J, Iwata S and Shimamura T.
Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone
Nat Commun. , 11 , 1 , 6442 (2020)
DOI: 10.1038/s41467-020-20221-0
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2020-12-24-2
A01: B01: A01 So Iwata A01 Norimichi Nomura B01 Eriko Nango -
YoshidaH, Park SY, Sakashita G, Nariai Y, Kuwasako K, Muto Y, Urano T, Obayashi E.
Elucidation of the aberrant 3 ́ splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun. , 11(1) , 4744 (2020)
DOI: https://doi.org/10.1038/s41467-020-18559-6
A01: A01 Sam-Yong Park -
Yun JH, Park JH, Jin Z, Ohki M, Wang Y, Lupala CS, Liu H, Park SY, Lee W
Structure- Based Functional Modification Study of a Cyanobacterial Chloride Pump for Transporting Multiple Anions.
J Mol Biol , 432 , 19 , 5273 (2020)
DOI: https://doi.org/10.1016/j.jmb.2020.07.016
A01: A01 Sam-Yong Park -
Wolff, A. M., Young, I. D., Sierra, R. G., Brewster, A. S., Martynowycz, M. W., Nango, E., Sugahara, M., Nakane, T., Ito, K., Aquila, A., Bhowmick, A., Biel, J. T., Carbajo, S., Cohen, A. E., Cortez, S., Gonzalez, A., Hino, T., Im, D., Koralek, J. D., Kubo, M., Lazarou, T. S., Nomura, T., Owada, S., Samelson, A. J., Tanaka, T., Tanaka, R., Thompson, E. M., van den Bedem, H., Woldeyes, R. A., Yumoto, F., Zhao, W., Tono, K., Boutet, S., Iwata, S., Gonen, T., Sauter, N. K., Fraser, J. S., Thompson, M. C.
Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals.
IUCrJ , 7 , 2 , 306-323 (2020)
DOI: https://doi.org/10.1107/S205225252000072X
A01: B01: C01: C01:2020 A01 So Iwata B01 Eriko Nango B01 Sigeki Owada C01 Minoru Kubo A01 Tomoya Hino -
Sakamoto S., Yamaura K., Numata T., Harada F., Amaike K., Inoue R., Kiyonaka S., Hamachi I.
Construction of a Fluorescent Screening System of Allosteric Modulators for the GABAA Receptor Using a Turn-On Probe.
ACS Central Science , 5 , 1541-1553 (2019)
DOI: 10.1021/acscentsci.9b00539
A01: A01 Shigeki Kiyonaka -
Shibayama N, Sato-Tomita A, Ohki M, Ichiyanagi K, Park SY.
Direct observation of ligand migration within human hemoglobin at work
Proc Natl Acad Sci U S A. , 117 , 9 , 4741-4748 (2020)
DOI: https://doi.org/10.1073/pnas.1913663117
A01: A01 Sam-Yong Park -
Yun JH, Ohki M, Park JH, Ishimoto N, Sato-Tomita A, Lee W, Jin Z, Tame JRH, Shibayama N, Park SY, Lee W.
Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family
Sci Adv. , 6 , 6 , eaay2042 (2020)
DOI: 10.1126/sciadv.aay2042
プレスリリース: https://www.yokohama-cu.ac.jp/news/2019/202002paku_SA.html
A01: A01 Sam-Yong Park -
Katayama T, Nozawa S, Umena Y, Lee S, Togashi T, Owada S, Yabashi M.
A versatile experimental system for tracking ultrafast chemical reactions with X-ray free-electron lasers
Struct. Dyn , 6 , 2019 (2019)
DOI: 10.1063/1.5111795
A01: B01: A01 Yasufumi Umena B01 Sigeki Owada B01 Tetsuo Katayama
書籍Books
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Nomura N, Nomura Y, Sato Y and Iwata S
Methods in Molecular Biology, Vol. 2247 “Multiprotein Complexes"
Springer page: 77-103 (2021)
A01: A01 So Iwata A01 Norimichi Nomura -
Nomura N, Nomura Y, Sato Y and Iwata S
Methods in Enzymology, Vol. 629, "Tumor Immunology and Immunotherapy – Molecular Methods" (Edited by Lorenzo Galluzzi, Nils-Petter Rudqvist)
Academic Press page: 383-399 (2019)
A01: A01 So Iwata A01 Norimichi Nomura -
Raymond G. Sierra, Uwe Weierstall, Dominik Oberthuer, Michihiro Sugahara, Eriko Nango, So Iwata and Alke Meents.
X-ray Free Electron Lasers - A Revolution in Structural Biology.
Springer page: 109-184 (2019)
A01: B01: A01 So Iwata B01 Eriko Nango -
山下恵太郎、溝端栄一
膜タンパク質工学ハンドブック 『X線結晶解析による新規構造の解明』
(株)エヌ・ティー・エス page: 27-33 (2020)
A01: A01 Keitaro Yamashita A01 Eiichi Mizohata -
溝端栄一、久保稔
膜タンパク質工学ハンドブック 『構造・解析―X線自由電子レーザーによる膜タンパク質の構造解析』
(株)エヌ・ティー・エス page: 11-15 (2020)
A01: C01: A01 Eiichi Mizohata C01 Minoru Kubo
学会発表Presentations, Lectures
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溝端栄一
銅含有亜硝酸還元酵素の動的結晶構造解析
第93回 日本生化学会大会, ( 2020 , 9 )
A01: A01 Eiichi Mizohata -
Eiichi Mizohata
Damage-free protein observation and structure determination using X-ray free electron laser
Pacifichem2020, ( 2021 , 12 )
A01: A01 Eiichi Mizohata -
末宗周憲、日野智也、永野真吾
アナモックス菌のラダラン脂質生合成の全容解明に向けた研究
第3回生合成リデザイン若手シンポジウム, ( 2019 , 8 )
A01: A01 Shingo Nagano -
上垣哲心、末宗周憲、日野智也、永野真吾
ラダラン脂質生合成アシルACP中間体の探索に向けた抗ACP抗体の作製
第92回日本生化学会大会, ( 2019 , 9 )
A01: A01 Shingo Nagano -
安田早希、藤山敬介、日野智也、水谷正治、永野真吾
トマチン16位水酸化酵素のX線結晶構造解析
令和元年度結晶学会, ( 2019 , 11 )
A01: A01 Shingo Nagano -
藤山 敬介, 畑田 珠希, 日野 智也, 水谷 正治, 永野 真吾
結晶構造に基づいたCYP90B1によるステロールC-22位水酸化の立体選択性の改変
植物化学調節学会第54回大会, ( 2019 , 11 )
A01: A01 Shingo Nagano -
清中 茂樹
New chemogenetic approaches for artificially controlling neurotransmitter receptor function in neuronal system
10th RSC-CSJ joint symposium -Chemistry for complex biological systems-, ( 2019 , 9 )
A01: A01 Shigeki Kiyonaka -
清中 茂樹
グルタミン酸受容体の精密動態を明らかにするためのケミカルラベル化法
第92回日本生化学会大会 , ( 2019 , 9 )
A01: A01 Shigeki Kiyonaka -
清中 茂樹
神経伝達物質受容体機能を解き明かすためのケミカルバイオロジー新技術
第72回日本薬理学会西南部会（次世代薬理学セミナー）, ( 2019 , 11 )
A01: A01 Shigeki Kiyonaka -
清中 茂樹
Coordination chemogenetics, a new technique for allosteric regulation of membrane receptors
The 50th NIPS International Symposium “MIRACLES” in Caridiovasucular Physology, ( 2019 , 12 )
A01: A01 Shigeki Kiyonaka -
溝端栄一
X線自由電子レーザーを応用したタンパク質の動的結晶構造解析
日本プロテオーム学会2019年大会 第70回日本電気泳動学会総会, ( 2019 , 7 )
A01: A01 Eiichi Mizohata