研究成果
Results list研究成果一覧
謝辞の記載についてAcknowledgement remarks
雑誌論文Papers
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Jinta Asami, Jae-Hyun Park, Yayoi Nomura, Chisa Kobayashi, Junki Mifune, Naito Ishimoto, Tomoko Uemura, Kehong Liu, Yumi Sato, Zhikuan Zhang, Masamichi Muramatsu, Takaji Wakita, David Drew, So Iwata, Toshiyuki Shimizu, Koichi Watashi, Sam-Yong Park, Norimichi Nomura, Umeharu Ohto
Structural basis of hepatitis B virus receptor binding
Nature Structural & Molecular Biology , 31 (2024)
DOI: 10.1038/s41594-023-01191-5
プレスリリース:
A01:計画研究 A01 岩田 想 A01 野村 紀通 A01 朴 三用 -
Han Ba Bui, Satoshi Watanabe, Norimichi Nomura, Kehong Liu, Tomoko Uemura, Michio Inoue, Akihisa Tsutsumi, Hiroyuki Fujita, Kengo Kinoshita, Yukinari Kato, So Iwata, Masahide Kikkawa, Kenji Inaba
Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn2+ uptake into the Golgi apparatus
Nature Communications , 14 , 4770 (2023)
DOI: 10.1038/s41467-023-40521-5
A01:計画研究 A01 岩田 想 A01 野村 紀通 -
Titouan Jaunet-Lahary, Tatsuro Shimamura, Masahiro Hayashi, Norimichi Nomura, Kouta Hirasawa, Tetsuya Shimizu, Masao Yamashita, Naotaka Tsutsumi, Yuta Suehiro, Keiichi Kojima, Yuki Sudo, Takashi Tamura, Hiroko Iwanari, Takao Hamakubo, So Iwata, Kei-ichi Okazaki, Teruhisa Hirai, Atsuko Yamashita
Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota
Nature Communications , 14 , 1730 (2023)
DOI: https://doi.org/10.1038/s41467-023-36883-5
A01:計画研究 A01 岩田 想 A01 野村 紀通 -
Muna Al-Habsi, Kenji Chamoto, Ken Matsumoto, Norimichi Nomura, Baihao Zhang, Yuki Sugiura, Kazuhiro Sonomura, Aprilia Maharani, Yuka Nakajima, Yibo Wu, Yayoi Nomura, Rosemary Menzies, Masaki Tajima, Koji Kitaoka, Yasuharu Haku, Sara Delghandi, Keiko Yurimoto, Fumihiko Matsuda, So Iwata, Toshihiko Ogura, Sidonia Fagarasan, Tasuku Honjo
Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice
Science , 378 , 6618 , eabj3510 (2022)
DOI: 10.1126/science.abj3510
A01:計画研究 A01 岩田 想 A01 野村 紀通 -
Ryoji Suno, Yukihiko Sugita, Kazushi Morimoto, Hiroko Takazaki, Hirokazu Tsujimoto, Mika Hirose, Chiyo Suno-Ikeda, Norimichi Nomura, Tomoya Hino, Asuka Inoue, Kenji Iwasaki, Takayuki Kato, So Iwata, Takuya Kobayashi
Structural insights into the G protein selectivity revealed by the human EP3-Gi signaling complex
Cell Reports , 40 , 11 , 111323 (2022)
DOI: 10.1016/j.celrep.2022.111323
プレスリリース:
A01:計画研究 A01 岩田 想 A01 野村 紀通 A01 日野 智也 -
Zhikuan Zhang, Norimichi Nomura, Yukiko Muramoto, Toru Ekimoto, Tomoko Uemura, Kehong Liu, Moeko Yui, Nozomu Kono, Junken Aoki, Mitsunori Ikeguchi, Takeshi Noda, So Iwata, Umeharu Ohto, Toshiyuki Shimizu
Structure of SARS-CoV-2 membrane protein essential for virus assembly
Nature Communications , 13 , 4399 (2022)
DOI: 10.1038/s41467-022-32019-3
プレスリリース:
A01:計画研究 A01 岩田 想 A01 野村 紀通 -
Jinta Asami, Kanako Terakado Kimura, Yoko Fujita-Fujiharu, Hanako Ishida, Zhikuan Zhang, Yayoi Nomura, Kehong Liu, Tomoko Uemura, Yumi Sato, Masatsugu Ono, Masaki Yamamoto, Takeshi Noda, Hideki Shigematsu, David Drew, So Iwata, Toshiyuki Shimizu, Norimichi Nomura, Umeharu Ohto
Structure of the bile acid transporter and HBV receptor NTCP
Nature , 606 , 7916 , 1021 (1026)
DOI: https://doi.org/10.1038/s41586-022-04845-4
A01:計画研究 B01:計画研究 A01 岩田 想 A01 野村 紀通 B01 山本 雅貴 -
Jae-Hyun Park, Masashi Iwamoto, Ji-Hye Yun, Tomomi Uchikubo-Kamo, Donghwan Son, Zeyu Jin, Hisashi Yoshida, Mio Ohki, Naito Ishimoto, Kenji Mizutani, Mizuki Oshima, Masamichi Muramatsu, Takaji Wakita, Mikako Shirouzu, Kehong Liu, Tomoko Uemura, Norimichi Nomura, So Iwata, Koichi Watashi, Jeremy R. H. Tame, Tomohiro Nishizawa, Weontae Lee, Sam-Yong Park
Structural insights into the HBV receptor and bile acid transporter NTCP
Nature , 606 , 7916 , 1027-1031 (2022)
DOI: https://doi.org/10.1038/s41586-022-04857-0
プレスリリース: https://www.yokohama-cu.ac.jp/news/2022/20220518parksamyong.html
A01:計画研究 A01 岩田 想 A01 野村 紀通 A01 朴 三用 -
Rei Matsuoka, Roman Fudim, Sukkyeong Jung, Chenou Zhang, Andre Bazzone, Yurie Chatzikyriakidou, Carol V. Robinson, Norimichi Nomura, So Iwata, Michael Landreh, Laura Orellana, Oliver Beckstein, David Drew
Structure, mechanism and lipid-mediated remodeling of the mammalian Na+/H+ exchanger NHA2
Nature Structural & Molecular Biology , 29 , 2 , 108-120 (2022)
DOI: 10.1038/s41594-022-00738-2
A01:計画研究 A01 岩田 想 A01 野村 紀通 -
Koichiro E. Kishi, Yoon Seok Kim, Masahiro Fukuda, Masatoshi Inoue, Tsukasa Kusakizako, Peter Y. Wang, Charu Ramakrishnan, Eamon F.X. Byrne, Elina Thadhani, Joseph M. Paggi, Toshiki E. Matsui, Keitaro Yamashita, Takashi Nagata, Masae Konno, Sean Quirin, Maisie Lo, Tyler Benster, Tomoko Uemura, Kehong Liu, Mikihiro Shibata, Norimichi Nomura, So Iwata, Osamu Nureki, Ron O. Dror, Keiichi Inoue, Karl Deisseroth, Hideaki E. Kato
Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine
Cell , 185 , 4 , 672-689 (2022)
DOI: 10.1016/j.cell.2022.01.007
プレスリリース: https://www.u-tokyo.ac.jp/focus/ja/press/z0109_00034.html
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Dmitry Ghilarov, Satomi Inaba-Inoue, Piotr Stepien, Feng Qu, Elizabeth Michalczyk, Zuzanna Pakosz, Norimichi Nomura, Satoshi Ogasawara, Graham Charles Walker, Sylvie Rebuffat, So Iwata, Jonathan Gardiner Heddle, Konstantinos Beis
Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides
Science Advances , 7 , 37 , abj5363 (2021)
DOI: 10.1126/sciadv.abj5363
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2021-09-09-0
A01:計画研究 A01 岩田 想 A01 野村 紀通 -
Hiroyuki H. Okamoto, Hirotake Miyauchi, Asuka Inoue, Francesco Raimondi, Hirokazu Tsujimoto, Tsukasa Kusakizako, Wataru Shihoya, Keitaro Yamashita, Ryoji Suno, Norimichi Nomura, Takuya Kobayashi, So Iwata, Tomohiro Nishizawa, Osamu Nureki
Cryo-EM structure of the human MT1–Gi signaling complex
Nature Structural & Molecular Biology , 28 (2021)
DOI: 10.1038/s41594-021-00634-1
プレスリリース: https://www.s.u-tokyo.ac.jp/ja/info/7508/
A01:計画研究 A01:2020年公募班 A01 岩田 想 A01 野村 紀通 A01 草木迫 司 A01 山下 恵太郎 A01 志甫谷 渉 -
Shingo Nojima, Yoko Fujita, Kanako Terakado Kimura, Norimichi Nomura, Ryoji Suno, Kazushi Morimoto, Masaki Yamamoto, Takeshi Noda, So Iwata, Hideki Shigematsu, Takuya Kobayashi
Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein
Structure , 29 , 3 , 252-260 (2021)
DOI: 10.1016/j.str.2020.11.007
A01:計画研究 B01:計画研究 A01 岩田 想 A01 野村 紀通 B01 山本 雅貴 -
Stephanie L. Neville, Jennie Sjöhamn, Jacinta A. Watts, Hugo MacDermott-Opeskin, Stephen J. Fairweather, Katherine Ganio, Alex Carey Hulyer, Aaron P. McGrath, Andrew J. Hayes, Tess R. Malcolm, Mark R. Davies, Norimichi Nomura, So Iwata, Megan L. O’Mara, Megan J. Maher, Christopher A. McDevitt
The structural basis of bacterial manganese import
Science Advances , 7 , 32 , eabg3980 (2021)
DOI: 10.1126/sciadv.abg3980
A01:計画研究 A01 岩田 想 A01 野村 紀通 -
Jin F, Sun M, Fujii T, Yamada Y, Wang J, Maturana AD, Wada M, Su S, Ma J, Takeda H, Kusakizako T, Tomita A, Nakada-Nakura Y, Liu K, Uemura T, Nomura Y, Nomura N, Ito K, Nureki O, Namba K, Iwata S, Yu Y, Hattori M
The structure of MgtE in the absence of magnesium provides new insights into channel gating
PLOS Biology , 19 , 4 , e3001231 (2021)
DOI: 10.1371/journal.pbio.3001231
A01:計画研究 A01 岩田 想 A01 野村 紀通 -
Matoba K, Kotani T, Tsutsumi A, Tsuji T, Mori T, Noshiro D, Sugita Y, Nomura N, Iwata S, Ohsumi Y, Fujimoto T, Nakatogawa H, Kikkawa M, Noda NN
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion
Nature Structural & Molecular Biology , 27 , 1185-1193 (2020)
DOI: 10.1038/s41594-020-00518-w
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2020-10-28
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Umeda R, Satouh Y, Takemoto M, Nakada-Nakura Y, Liu K, Yokoyama T, Shirouzu M, Iwata S, Nomura N, Sato K, Ikawa M, Nishizawa T, Nureki O
Structural insights into tetraspanin CD9 function
Nature Communications , 11 , 1606 (2020)
DOI: 10.1038/s41467-020-15459-7
A01:計画研究 A01 岩田 想 A01 野村 紀通 -
Asada H, Inoue A, Ngako Kadji FM, Hirata K, Shiimura Y, Im D, Shimamura T, Nomura N, Iwanari H, Hamakubo T, Kusano-Arai O, Hisano H, Uemura T, Suno C, Aoki J and Iwata S
The crystal structure of angiotensin II type 2 receptor with endogenous peptide hormone
Structure , 28 , 4 , 418-425 (2020)
DOI: 10.1016/j.str.2019.12.003
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2020-01-22-1
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Kinjo T, Terai K, Horita S, Nomura N, Sumiyama K, Togashi K, Iwata S and Matsuda M.
FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics
Nature Methods , 16 , 1029-1036 (2019)
DOI: 10.1038/s41592-019-0541-5
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2019-09-10
A01:計画研究 A01 岩田 想 A01 野村 紀通 -
Im D, Inoue A, Fujiwara T, Nakane T, Yamanaka Y, Uemura T, Mori C, Shiimura Y, Kimura KT, Asada H, Nomura N, Tanaka T, Yamashita A, Nango E, Tono K, Kadji FMN, Aoki J, Iwata S and Shimamura T.
Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone
Nat Commun. , 11 , 1 , 6442 (2020)
DOI: 10.1038/s41467-020-20221-0
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2020-12-24-2
A01:計画研究 B01:計画研究 A01 岩田 想 A01 野村 紀通 B01 南後 恵理子
書籍Books
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Nomura N, Nomura Y, Sato Y and Iwata S
Methods in Molecular Biology, Vol. 2247 “Multiprotein Complexes"
Springer page: 77-103 (2021)
A01:計画研究 A01 岩田 想 A01 野村 紀通 -
Nomura N, Nomura Y, Sato Y and Iwata S
Methods in Enzymology, Vol. 629, "Tumor Immunology and Immunotherapy – Molecular Methods" (Edited by Lorenzo Galluzzi, Nils-Petter Rudqvist)
Academic Press page: 383-399 (2019)
A01:計画研究 A01 岩田 想 A01 野村 紀通
学会発表Presentations, Lectures
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