研究成果

Results list研究成果一覧

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Categoryカテゴリー

Type班タイプ

Member研究者名

Keywordタイトルキーワード

謝辞の記載についてAcknowledgement remarks

雑誌論文Papers

Hosaka T, Nomura T, Kubo M, Nakane T, Fangjia L, Sekine SI, Ito T, Murayama K, Ihara K, Ehara H, Kashiwagi K, Katsura K, Akasaka R, Hisano T, Tanaka T, Tanaka R, Arima T, Yamashita A, Sugahara M, Naitow H, Matsuura Y, Yoshizawa S, Tono K, Owada S, Nureki O, Kimura-Someya T, Iwata S, *Nango E, *Shirouzu M.
Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers
Proc Natl Acad Sci U S A , 119 , 9 , e2117433119 (2022)
DOI: https://doi.org/10.1073/pnas.2117433119
プレスリリース: https://www.kyoto-u.ac.jp/ja/research-news/2022-02-28-2
A01:計画研究 B01:計画研究 C01:計画研究 A01:2020年公募班 A01 岩田　想 B01 南後　恵理子 B01 大和田　成起 C01 久保　稔 A01 保坂　俊彰
Kiichi Hirazawa, Michihiro Tateyama, Yoshihiro Kubo, Takushi Shimomura,
Phosphoinositide regulates dynamic movement of the S4 voltage sensor in the second repeat in two-pore channel 3
J Biol Chem. , 297 , 6 , 101425 (2021)
DOI: 10.1016/j.jbc.2021.101425
A01:2020年公募班 A01 下村　拓史
*Katayama K, Suzuki K, Suno R, Kise R, Tsujimoto H, Iwata S, Inoue A, Kobayashi T & *Kandori H.
Vibrational spectroscopy analysis of ligand efficacy in human M2 muscarinic acetylcholine receptor (M2R)
Communications Biology , 4 , 1321 (2021)
DOI: https://doi.org/10.1038/s42003-021-02836-1
プレスリリース: https://www.nitech.ac.jp/news/press/2021/9297.html
A01:計画研究 A01:2020年公募班 A01 岩田　想 A01 片山　耕大
1. *Murakaw T, Suzuki M, Arima T, Sugahara M, Tanaka T, Tanaka R, Iwata S, Nango E, Tono K, Hayashi H, Fukui K, Yano T, Tanizawah K and *Okajima T.
Microcrystal preparation for serial femtosecond X-ray crystallography of bacterial copper amine oxidase
Acta Crystallographica Section F. , 77 (2021)
DOI: https://doi.org/10.1107/S2053230X21008967
A01:計画研究 B01:計画研究 A01:2020年公募班 A01 岩田　想 B01 南後　恵理子 A01 村川　武志
Hiroyuki H. Okamoto, Hirotake Miyauchi, Asuka Inoue, Francesco Raimondi, Hirokazu Tsujimoto, Tsukasa Kusakizako, Wataru Shihoya, Keitaro Yamashita, Ryoji Suno, Norimichi Nomura, Takuya Kobayashi, So Iwata, Tomohiro Nishizawa, Osamu Nureki
Cryo-EM structure of the human MT1–Gi signaling complex
Nature Structural & Molecular Biology , 28 (2021)
DOI: 10.1038/s41594-021-00634-1
プレスリリース: https://www.s.u-tokyo.ac.jp/ja/info/7508/
A01:計画研究 A01:2020年公募班 A01 岩田　想 A01 野村　紀通 A01 草木迫司 A01 山下　恵太郎 A01 志甫谷　渉
Fujiyama K, Kato N, Re S, Kinugasa K, Watanabe K, Takita R, Nogawa T, Hino T, Osada H, Sugita Y, Takahashi S, Nagano S.
Molecular basis for two stereoselective Diels-Alderases that produce decalin skeletons.
Angew Chem Int Ed. (2021)
DOI: https://doi.org/10.1002/anie.202106186
プレスリリース: https://www.tottori-u.ac.jp/item/18745.htm
A01:計画研究 A01:2020年公募班 A01 永野　真吾 A01 日野　智也
Demura K, Kusakizako T, Shihoya W, Hiraizumi M, Nomura K, Shimada H, Yamashita K, Nishizawa T, Taruno A, Nureki O.
Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies
Sci Adv. , 6 , 29 , eaba8105 (2020)
DOI: 10.1126/sciadv.aba8105.
A01:計画研究 A01:2020年公募班 A01 草木迫司 A01 志甫谷　渉
Fukuhara S, Kobayashi K, Kusakizako T, Iida W, Kato M, Shihoya W, Nureki O.
Structure of the human secretin receptor coupled to an engineered heterotrimeric G protein
Biochem Biophys Res Commun , 533 , 4 , 861-866 (2020)
DOI: 10.1016/j.bbrc.2020.08.042.
A01:計画研究 A01:2020年公募班 A01 草木迫司 A01 志甫谷　渉
Oda K, Nomura T, Nakane T, Yamashita K, Inoue K, Ito S, Vierock J, Hirata K, Maturana AD, Katayama K, Ikuta T, Ishigami I, Izume T, Umeda R, Eguma R, Oishi S, Kasuya G, Kato T, Kusakizako T, Shihoya W, Shimada H, Takatsuji T, Takemoto M, Taniguchi R, Tomita A, Nakamura R, Fukuda M, Miyauchi H, Lee Y, Nango E, Tanaka R, Tanaka T, Sugahara M, Kimura T, Shimamura T, Fujiwara T, Yamanaka Y, Owada S, Joti Y, Tono K, Ishitani R, Hayashi S, Kandori H, Hegemann P, Iwata S, Kubo M, Nishizawa T, Nureki O.
Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin
elife , 23 , e62389 (2021)
DOI: 10.7554/eLife.62389
プレスリリース: https://www.s.u-tokyo.ac.jp/ja/press/2021/7284/
A01:計画研究 B01:計画研究 C01:計画研究 A01:2020年公募班 C01:2020年公募班 A01 岩田　想 A01 草木迫司 B01 南後　恵理子 B01 大和田　成起 C01 久保　稔 C01 木村　哲就 A01 志甫谷　渉 A01 片山　耕大 C01 林　重彦
Tatsuki Tanaka, Manish Singh, Wataru Shihoya, Keitaro Yamashita, Hideki Kandori, Osamu Nureki
Structural basis for unique color tuning mechanism in heliorhodopsin
Biochem Biophys Res Commun , 533 , 3 , 262-267 (2020)
DOI: 10.1016/j.bbrc.2020.06.124
A01:2020年公募班 A01 志甫谷　渉
Akimitsu Higuchi, Wataru Shihoya, Masae Konno, Tatsuya Ikuta, Hideki Kandori, Keiichi Inoue, Osamu Nureki
Crystal structure of schizorhodopsin reveals mechanism of inward proton pumping
Proceedings of the National Academy of Sciences of the United States of America , 118 , 14 , e2016328118 (2021)
DOI: https://doi.org/10.1073/pnas.2016328118
プレスリリース: https://www.s.u-tokyo.ac.jp/ja/press/2021/7261/
A01:2020年公募班 A01 志甫谷　渉
Takahashi S, Nambu S, Matsui T, Fujii H, Ishikawa H, Mizutani Y, Tsumoto K, Ikeda-Saito M.
Unique Electronic Structures of the Highly Ruffled Hemes in Heme-Degrading Enzymes of Staphylococcus aureus, IsdG and IsdI, by Resonance Raman and Electron Paramagnetic Resonance Spectroscopies.
Biochemistry , 59 , 40 , 3918-3928 (2020)
DOI: 10.1021/acs.biochem.0c00731
A01:2020年公募班 A01 松井　敏高
Kazuki Matsumura, Takushi Shimomura, Yoshihiro Kubo, Takayuki Oka, Naohiro Kobayashi, Shunsuke Imai, Naomi Yanase, Madoka Akimoto, Masahiro Fukuda, Mariko Yokogawa, Kazuyoshi Ikeda, Jun-Ichi Kurita, Yoshifumi Nishimura, Ichio Shimada, Masanori Osawa
Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization
BMC Mol Cell Biol. , 22 , 3 (2021)
DOI: https://doi.org/10.1186/s12860-020-00337-3
A01:2020年公募班 A01 下村　拓史
Takeda, H., Kimura, T., Nomura, T., Horitani, M., Yokota, A., Matsubayashi, A., Ishii, S., Shiro, Y., Kubo, M., Tosha, T.
Timing of NO Binding and Protonation in the Catalytic Reaction of Bacterial Nitric Oxide Reductase as Established by Time-Resolved Spectroscopy.
Bull. Chem. Soc. Japan , 93 , 7 , 825-833 (2020)
DOI: https://doi.org/10.1246/bcsj.20200038
C01:計画研究 A01:2020年公募班 C01 久保　稔 C01 木村　哲就 A01 當舎　武彦
Suga, M., Akita, F., Yamashita, K., Nakajima, Y., Ueno, G., Li, H., Yamane, T., Hirata, K., Umena, Y., Yonekura, S., Yu, L.-J., Murakami, H., Nomura, T., Kimura, T., Kubo, M., Baba, S., Kumasaka, T., Tono, K., Yabashi, M., Isobe, H., Yamaguchi, K. Yamamoto, M., Ago, H., Shen, J.-R.
An oxyl/oxo mechanism for oxygen-oxygen coupling in PSII revealed by an X-ray free electron laser.
Science , 366 , 6463 , 334-338 (2019)
DOI: 10.1126/science.aax6998
A01:計画研究 B01:計画研究 C01:計画研究 A01:2020年公募班 A01 梅名　泰史 B01 山本　雅貴 B01 熊坂　崇 C01 久保　稔 C01 木村　哲就 A01 菅　倫寛
Tatsuya Ikuta, Wataru Shihoya, Masahiro Sugiura, Kazuho Yoshida, Masahito Watari, Takaya Tokano, Keitaro Yamashita, Kota Katayama, Satoshi P. Tsunoda, Takayuki Uchihashi, Hideki Kandori & Osamu Nureki
Structural insights into the mechanism of rhodopsin phosphodiesterase
Nature Communications , 11 , 5605 (2020)
DOI: doi: 10.1038/s41467-020-19376-7
プレスリリース: https://www.s.u-tokyo.ac.jp/ja/press/2020/7094/
A01:2020年公募班 A01 志甫谷　渉 A01 片山　耕大
H. Shimada, T. Kusakizako, T. H. D. Nguyen, T. Nishizawa, T. Hino, M. Tominaga and O. Nureki.
The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism
Nature Struct. Mol. Biol. (2020)
DOI: https://doi.org/10.1038/s41594-020-0439-z
A01:2020年公募班 A01 日野　智也

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